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1

Formulation, Biological and Pharmacokinetic Studies of Sucrose Ester-Stabilized Nanosuspensions of Oleanolic Acid

Wenji Li, Surajit Das, Ka-yun Ng, Paul W. S. Heng

Journal:

Pharmaceutical Research

Année:

2011

Langue:

english

Fichier:

PDF, 1.50 MB

english, 2011

2

Carrier-Mediated Uptake of Rhodamine 123: Implications on Its Use for MDR Research

Cheong-Weon Cho, Yang Liu, Xiangdong Yan, Thomas Henthorn, Ka-Yun Ng

Journal:

Biochemical and Biophysical Research Communications

Année:

2000

Langue:

english

Fichier:

PDF, 216 KB

english, 2000

3

Polyethyleneimine-modified pectin beads for colon-specific drug delivery: In vitro and in vivo implications

Das, Surajit, Chaudhury, Anumita, Ng, Ka-Yun

Journal:

Journal of Microencapsulation

Année:

2011

Langue:

english

Fichier:

PDF, 824 KB

english, 2011

4

ChemInform Abstract: Therapeutic Ultrasound: Its Application in Drug Delivery

Ka-yun Ng, Yang Liu

Journal:

Année:

2002

Fichier:

PDF, 23 KB

2002

5

Hydrophobic ion pairing of isoniazid using a prodrug approach

Huiyu Zhou, Corinne Lengsfeld, David J. Claffey, James A. Ruth, Brooks Hybertson, Theodore W. Randolph, Ka-Yun Ng, Mark C. Manning

Journal:

Journal of Pharmaceutical Sciences

Année:

2002

Langue:

english

Fichier:

PDF, 122 KB

english, 2002

6

Effect of heat preconditioning on the uptake and permeability of R123 in brain microvessel endothelial cells during mild heat treatment

Ka-Yun Ng, Cheong-Weon Cho, Thomas K. Henthorn, Robert L. Tanguay

Journal:

Journal of Pharmaceutical Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 201 KB

english, 2004

7

Resveratrol-loaded calcium-pectinate beads: Effects of formulation parameters on drug release and bead characteristics

Surajit Das, Ka-Yun Ng

Journal:

Journal of Pharmaceutical Sciences

Année:

2010

Langue:

english

Fichier:

PDF, 458 KB

english, 2010

8

Impact of glutaraldehyde on in vivo colon-specific release of resveratrol from biodegradable pectin-based formulation

Surajit Das, Ka-Yun Ng

Journal:

Journal of Pharmaceutical Sciences

Année:

2010

Langue:

english

Fichier:

PDF, 278 KB

english, 2010

9

Polyporenic acid C induces caspase-8-mediated apoptosis in human lung cancer A549 cells

Hui Ling, Liang Zhou, Xiaobin Jia, Leslie A. Gapter, Rajesh Agarwal, Ka-yun Ng

Journal:

Molecular Carcinogenesis

Année:

2009

Langue:

english

Fichier:

PDF, 303 KB

english, 2009

10

Pachymic acid inhibits cell growth and modulates arachidonic acid metabolism in nonsmall cell lung cancer A549 cells

Hui Ling, Xiaobin Jia, Yaochun Zhang, Leslie A. Gapter, Yin-shan Lim, Rajesh Agarwal, Ka-yun Ng

Journal:

Molecular Carcinogenesis

Année:

2010

Langue:

english

Fichier:

PDF, 347 KB

english, 2010

11

Therapeutic ultrasound: Its application in drug delivery

Ka-yun Ng, Yang Liu

Journal:

Medicinal Research Reviews

Année:

2002

Langue:

english

Fichier:

PDF, 241 KB

english, 2002

12

Colon-specific delivery of resveratrol: Optimization of multi-particulate calcium-pectinate carrier

Surajit Das, Ka-Yun Ng

Journal:

International Journal of Pharmaceutics

Année:

2010

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2010

13

Preparation and evaluation of zinc–pectin–chitosan composite particles for drug delivery to the colon: Role of chitosan in modifying in vitro and in vivo drug release

Surajit Das, Anumita Chaudhury, Ka-Yun Ng

Journal:

International Journal of Pharmaceutics

Année:

2011

Langue:

english

Fichier:

PDF, 835 KB

english, 2011

14

Quantification of isoniazid and acetylisoniazid in rat plasma and alveolar macrophages by liquid chromatography–tandem mass spectrometry with on-line extraction

Ka-yun Ng, Huiyu Zhou, Yan Ling Zhang, Brooks Hybertson, Theodore Randolph, Uwe Christians

Journal:

Journal of Chromatography B

Année:

2007

Langue:

english

Fichier:

PDF, 1.72 MB

english, 2007

15

Alveolar macrophage cell line is not activated by exposure to polymeric microspheres

Ka-yun Ng, Kathleen A. Stringer, Zoe Cohen, Robert Serravo, Bin Tian, Jeffrey D. Meyer, Richard Falk, Theodore Randolph, Mark C. Manning, David C. Thompson

Journal:

International Journal of Pharmaceutics

Année:

1998

Langue:

english

Fichier:

PDF, 431 KB

english, 1998

16

The effects of polyethyleneglycol (PEG)-derived lipid on the activity of target-sensitive immunoliposome

Ka-yun Ng, Limin Zhao, Yang Liu, Mrinal Mahapatro

Journal:

International Journal of Pharmaceutics

Année:

2000

Langue:

english

Fichier:

PDF, 191 KB

english, 2000

17

Use of circular dichroism spectroscopy in determining the conformation of a monoclonal antibody prior to its incorporation in an immunoliposome

Ka-yun Ng, Limin Zhao, Jeffrey D Meyer, Lana Rittmann-Grauer, Mark C Manning

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Année:

1997

Langue:

english

Fichier:

PDF, 151 KB

english, 1997

18

Pachymic acid impairs breast cancer cell invasion by suppressing nuclear factor-κB-dependent matrix metalloproteinase-9 expression

Hui Ling, Yaochun Zhang, Ka-Yun Ng, Eng-Hui Chew

Journal:

Breast Cancer Research and Treatment

Année:

2011

Langue:

english

Fichier:

PDF, 606 KB

english, 2011

19

TGF-β2 inhibition augments the effect of tumor vaccine and improves the survival of animals with pre-established brain tumors

Yang Liu, Qing Wang, B. K. Kleinschmidt-DeMasters, Alex Franzusoff, Ka-yun Ng, Kevin O. Lillehei

Journal:

Journal of Neuro-Oncology

Année:

2007

Langue:

english

Fichier:

PDF, 565 KB

english, 2007

20

The Impact of Aqueous Solubility and Dose on the Pharmacokinetic Profiles of Resveratrol

Surajit Das, Hai-Shu Lin, Paul C. Ho, Ka-Yun Ng

Journal:

Pharmaceutical Research

Année:

2008

Langue:

english

Fichier:

PDF, 183 KB

english, 2008

21

The Impact of Aqueous Solubility and Dose on the Pharmacokinetic Profiles of Resveratrol

Surajit Das, Hai-Shu Lin, Paul C. Ho, Ka-Yun Ng

Journal:

Pharmaceutical Research

Année:

2008

Fichier:

PDF, 37 KB

2008

22

Mixtures of tight-binding enzyme inhibitors. Kinetic analysis by a recursive rate equation

Petr Kuzmič, Ka-Yun Ng, Timothy D. Heath

Journal:

Analytical Biochemistry

Année:

1992

Langue:

english

Fichier:

PDF, 742 KB

english, 1992

23

Biochemical characteristics of a primary blood-brain barrier cell culture system as a function of the activity of the proteases used in tissue disaggregation

Ka-yun Ng, John M. Schallenkemp

Journal:

Journal of Neuroscience Methods

Année:

1996

Langue:

english

Fichier:

PDF, 779 KB

english, 1996

24

LDL Induced Association of Anionic Liposomes with Cells and Delivery of Contents as Shown by the Increase in Potency of Liposome Dependent Drugs

Ketan Amin, Ka-Yun Ng, Carolyn S. Brown, Maria S. Bruno, Timothy D. Heath

Journal:

Pharmaceutical Research

Année:

2001

Langue:

english

Fichier:

PDF, 175 KB

english, 2001

25

Ultrasound-Induced Hyperthermia Increases Cellular Uptake and Cytotoxicity of P-Glycoprotein Substrates in Multi-Drug Resistant Cells

Yang Liu, Cheong-Weon Cho, Xiangdong Yan, Thomas K. Henthorn, Kevin O. Lillehei, Wesley N. Cobb, Ka-yun Ng

Journal:

Pharmaceutical Research

Année:

2001

Langue:

english

Fichier:

PDF, 518 KB

english, 2001

26

Hydrogen Bonding Potential as a Determinant of thein Vitroandin SituBlood–Brain Barrier Permeability of Peptides

Elsbeth G. Chikhale, Ka-Yun Ng, Philip S. Burton, Ronald T. Borchardt

Journal:

Pharmaceutical Research

Année:

1994

Fichier:

PDF, 1.35 MB

1994

27

Ultrasound-Induced Mild Hyperthermia as a Novel Approach to Increase Drug Uptake in Brain Microvessel Endothelial Cells

Cheong-Weon Cho, Yang Liu, Wesley N. Cobb, Thomas K. Henthorn, Kevin Lillehei, Uwe Christians, Ka-Yun Ng

Journal:

Pharmaceutical Research

Année:

2002

Langue:

english

Fichier:

PDF, 177 KB

english, 2002

28

Interaction of Oxazaphosphorines with Multidrug Resistance-Associated Protein 4 (MRP4)

Jing Zhang, Ka-Yun Ng, Paul C. Ho

Journal:

The AAPS Journal

Année:

2010

Langue:

english

Fichier:

PDF, 265 KB

english, 2010

29

Formulation and Optimization of Zinc-Pectinate Beads for the Controlled Delivery of Resveratrol

Surajit Das, Ka-Yun Ng, Paul C. Ho

Journal:

AAPS PharmSciTech

Année:

2010

Langue:

english

Fichier:

PDF, 464 KB

english, 2010

30

Characterization of the unstirred water layer in cultured brain microvessel endothelial cells

Ka-yun Ng, George Grass, Hank Lane, Ronald T. Borchardt

Journal:

In Vitro Cellular & Developmental Biology - Animal

Année:

1993

Langue:

english

Fichier:

PDF, 298 KB

english, 1993

31

Relationship between genotype and enzyme activity of glutathione S-transferases M1 and P1 in Chinese

Shi-long Zhong, Shu-Feng Zhou, Xiao Chen, Sui Yung Chan, Eli Chan, Ka-Yun Ng, Wei Duan, Min Huang

Journal:

European Journal of Pharmaceutical Sciences

Année:

2006

Langue:

english

Fichier:

PDF, 266 KB

english, 2006

32

Microparticle-based lung delivery of INH decreases INH metabolism and targets alveolar macrophages

Huiyu Zhou, Yanling Zhang, Danielle L. Biggs, Mark C. Manning, Theodore W. Randolph, Uwe Christians, Brooks M. Hybertson, Ka-yun Ng

Journal:

Journal of Controlled Release

Année:

2005

Langue:

english

Fichier:

PDF, 204 KB

english, 2005

33

In vitro and in vivo evaluation of the effects of PLA microparticle crystallinity on cellular response

Danielle L Biggs, Corinne S Lengsfeld, Brooks M Hybertson, Ka-yun Ng, Mark C Manning, Theodore W Randolph

Journal:

Journal of Controlled Release

Année:

2003

Langue:

english

Fichier:

PDF, 558 KB

english, 2003

34

Enhancing transdermal drug transport with low-frequency ultrasound

Journal:

Drug Discovery Today

Année:

2004

Langue:

english

Fichier:

PDF, 82 KB

english, 2004

35

Overcoming MDR by Ultrasound-Induced Hyperthermia and P-Glycoprotein Modulation

Yang Liu, Kevin Lillehei, Wesley N. Cobb, Uwe Christians, Ka-yun Ng

Journal:

Biochemical and Biophysical Research Communications

Année:

2001

Langue:

english

Fichier:

PDF, 183 KB

english, 2001

36

Liposome-dependent delivery of pteridine antifolates: a two-compartment growth inhibition assay for evaluating drug leakage and metabolism

Ka-yun Ng, Timothy D. Heath

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

1989

Langue:

english

Fichier:

PDF, 1.04 MB

english, 1989

37

Induction of apoptosis in prostate cancer cells by pachymic acid from Poria cocos

Leslie Gapter, Zaisen Wang, Jan Glinski, Ka-yun Ng

Journal:

Biochemical and Biophysical Research Communications

Année:

2005

Langue:

english

Fichier:

PDF, 458 KB

english, 2005

38

Corrigendum to “Induction of apoptosis in prostate cancer cells by pachymic acid from Poria cocos” [Biochem. Biophys. Res. Commun. 332 (2005) 1153–1161]

Leslie Gapter, Zaisen Wang, Jan Glinski, Ka-yun Ng

Journal:

Biochemical and Biophysical Research Communications

Année:

2006

Langue:

english

Fichier:

PDF, 54 KB

english, 2006

39

Pim-1 kinase expression during murine mammary development

Leslie A. Gapter, Nancy S. Magnuson, Ka-yun Ng, Howard L. Hosick

Journal:

Biochemical and Biophysical Research Communications

Année:

2006

Langue:

english

Fichier:

PDF, 483 KB

english, 2006

40

S-Allylcysteine reduces breast tumor cell adhesion and invasion

Leslie A. Gapter, Ong Zhan Yuin, Ka-yun Ng

Journal:

Biochemical and Biophysical Research Communications

Année:

2008

Langue:

english

Fichier:

PDF, 601 KB

english, 2008

41

Biotin transport in a human intestinal epithelial cell line (Caco-2)

Ka-Yun Ng, Ronald T. Borchardt

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 426 KB

english, 1993

42

Antioxidant and Nrf2 inducing activities of luteolin, a flavonoid constituent in Ixeris sonchifolia Hance, provide neuroprotective effects against ischemia-induced cellular injury

Zhang, Yao-Chun, Gan, Fei-Fei, Shelar, Sandeep Balu, Ng, Ka-Yun, Chew, Eng-Hui

Journal:

Food and Chemical Toxicology

Année:

2013

Langue:

english

Fichier:

PDF, 1.97 MB

english, 2013

43

Design of a pectin-based microparticle formulation using zinc ions as the cross-linking agent and glutaraldehyde as the hardening agent for colonic-specific delivery of resveratrol: In vitro and in vivo evaluations

Das, Surajit, Ng, Ka-Yun, Ho, Paul C.

Journal:

Journal of Drug Targeting

Année:

2011

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2011

44

QUANTIFICATION OF TRANS -RESVERATROL IN RAT PLASMA BY A SIMPLE AND SENSITIVE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY METHOD AND ITS APPLICATION IN PRE-CLINICAL STUDY

Das, Surajit, Ng, Ka-Yun

Journal:

Journal of Liquid Chromatography & Related Technologies

Année:

2011

Langue:

english

Fichier:

PDF, 631 KB

english, 2011

45

Sesquiterpene lactones from Ixeris sonchifolia Hance and their cytotoxicities on A549 human non-small cell lung cancer cells

Zhang, Yao-Chun, Zhou, Liang, Ng, Ka-Yun

Journal:

Journal of Asian Natural Products Research

Année:

2009

Langue:

english

Fichier:

PDF, 113 KB

english, 2009

46

Association of Methotrexate Encapsulated in Negatively Charged Liposomes with Cells at Nanomolar Lipid Concentrations

Ng, Ka-Yun, Heath, Timothy D.

Journal:

Journal of Liposome Research

Année:

1992

Langue:

english

Fichier:

PDF, 937 KB

english, 1992

47

Topotecan Is a Substrate for Multidrug Resistance Associated Protein 4

Tian, Quan, Zhang, Jing, Chan, Sui, Chin Tan, Theresa, Duan, Wei, Huang, Min, Zhu, Yi, Chan, Eli, Yu, Qiang, Nie, Yu, Chi-Liu Ho, Paul, Qi Li, Bentham Science Publisher, Ka-Yun Ng, Bentham Science Pub

Journal:

Current Drug Metabolism

Année:

2006

Langue:

english

Fichier:

PDF, 233 KB

english, 2006

48

Pharmacokinetic Mechanisms for Reduced Toxicity of Irinotecan by Coadministered Thalidomide

Yang, Xiao-Xia, Hu, Ze-Ping, Chan, Sui, Duan, Wei, Ho, Paul, Boelsterli, Urs, Ng, Ka-Yun, Chan, Eli, Bian, Jin-Song, Chen, Yu-Zong, Huang, Min, Zhou, >

Journal:

Current Drug Metabolism

Année:

2006

Langue:

english

Fichier:

PDF, 703 KB

english, 2006

49

Time course analysis and modulating effects of established brain tumor on active-specific immunotherapy

Liu, Yang, Ng, Ka-Yun, Lillehei, Kevin O.

Journal:

Neurosurgical FOCUS

Année:

2000

Langue:

english

Fichier:

PDF, 672 KB

english, 2000

50

Competitive Substrates for P-Glycoprotein and Organic Anion Protein Transporters Differentially Reduce Blood Organ Transport of Fentanyl and Loperamide: Pharmacokinetics and Pharmacodynamics in Sprague-Dawley Rats

Elkiweri, Iman A., Zhang, Yan Ling, Christians, Uwe, Ng, Ka-Yun, Tissot van Patot, Martha C., Henthorn, Thomas K.

Journal:

Anesthesia & Analgesia

Année:

2009

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2009